Creatine is a naturally occurring compound made from three amino acids. Your liver, kidneys and pancreas produce it, and it's also found in foods like red meat.

While your body makes creatine on its own, and you can get some through your diet, those amounts typically aren't enough to provide the performance benefits seen with supplementation.

Best known for helping muscles work harder during high-intensity exercise, creatine is one of the most researched sports nutrition supplements available. The most studied form is creatine monohydrate, which has been shown to improve exercise performance and increase lean muscle mass when paired with resistance training.

"There are three different forms that creatine can come in. It can come in a pill (capsule form), it can come in gummy form, or a powder form. There are different types of creatine; the most well-studied form is creatine monohydrate," says Gabrielle Raucci, outpatient clinical oncology dietitian with OSF HealthCare Cancer Institute. "All the studies we've seen say the best form is going to be powder. It's better absorbed by your body, and you can just take a scoop of it, add it to water and shake it up really well."

Most adults who choose to supplement should aim for about three to five grams per day, Raucci says.

Emerging research also suggests creatine may have benefits beyond muscle health. Recent studies have found promising evidence that it may help support brain energy metabolism and cognitive function, although researchers say more studies are needed to understand its long-term effects in healthy adults.

For people with cancer, however, timing matters.

"The main thing we focus on is that if you're undergoing an active treatment, like chemotherapy or immunotherapy, the kidneys can sometimes take a hit with those treatments. When your body breaks down creatine, it breaks it into a byproduct called creatinine," Raucci says. "When your oncologists are closely looking at your blood levels, we wouldn't want to take a supplement that could potentially bump your creatinine. So, make sure to talk with your care team if you're on an active treatment and you want to use one of these supplements. Because it could potentially affect your kidneys."

For cancer survivors who have completed treatment, creatine may be an option to help rebuild muscle mass, particularly when combined with regular strength training.

"If you're in survivorship and are looking to build your lean body mass up, it could be a safe supplement," Raucci says. "Check with your care team, they'll double-check your medications and see if it's something to build yourself up after treatment."

As with any supplement, people undergoing cancer treatment or managing other medical conditions should talk with their health care team before starting creatine to ensure it's appropriate for their individual situation.

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Now, emerging research continues to point to multiple factors of why hundreds of thousands of people worldwide are dying from the disease each year. The World Cancer Research Fund (WCRF) reports lung cancer as the most common cancer across the globe, attributing most of the cases to people in China, the United States and Japan from data released in 2022. The Journal of Thoracic Oncology says 1.8 million people die each year from lung cancer.

Between 10-20% of patients diagnosed with lung cancer are non-smokers.

In part one of this two-part series, Jun Zhang, MD, PhD, a thoracic oncologist and the vice president of oncology research with OSF HealthCare Cancer Institute, discusses five main reasons that patients who do not smoke are being diagnosed with lung cancer. Part one discussed both PM2.5 (Particulate matter) and radon levels being major causes of lung cancer among nonsmokers, while this article will dive into the next three categories.

#3: Cooking fumes leading to lung cancer

The World Health Organization (WHO) reports that each year, 2.9 million people die prematurely from illnesses caused by household air pollution, specifically by the “incomplete combustion of solid fuels and kerosene used for cooking.”

Of those deaths, 6% are from lung cancer, the WHO says, adding that roughly 11% of lung cancer deaths in adults are attributed to “carcinogens from household air pollution caused by using kerosene or solid fuels like wood, charcoal or coal for household energy needs.”

"This is one of the reasons there's a higher incidence among Asian people, because of cooking style and the importance of food," Dr. Zhang says. "Over there, the way we cook delicious food is using the really hot wok (large bowl-shaped pan used for high-heat cooking) as the way to cook. Especially if the cooking involves using animal fat, it can create droplets (fumes), that can be inhaled and cause problems." 

#4: Secondhand smoking

Just as there is no safe level of smoking, the same can be said for secondhand smoke (SHS). The U.S. Centers for Disease Control & Prevention (CDC) says even brief exposure to SHS can be harmful. This should be a wakeup call to both smokers and those who are around smokers, and lung cancer isn’t the only health concern.

The CDC reports other health problems that can be caused by secondhand smoke (in adults who don’t smoke) are coronary heart disease, stroke, as well as reproductive health effects in women. For infants and kids, SHS can cause sudden infant death syndrome (SIDS), respiratory infections, ear infections and asthma attacks.

Especially in the 1940s through 60s, smoking was seen more broadly as "cool" and was a norm in many American households. So, secondhand smoking, Dr. Zhang says, is another major contributor to non-smoking lung cancer diagnoses. 

"Whether it's a parent smoking or a coworker smoking, this leads to indoor air pollution," Dr. Zhang points out. 

SHS causes more than 7,300 lung cancer deaths each year in American adults who don’t smoke and increases the risk of lung cancer in adult non-smokers by 20-30%.

#5: Genetic predispositions

Your genes can play a role in your cancer risk as well, Dr. Zhang says. A family history of lung cancer in a first-degree relative account for approximately 25% of attributable risk in never-smokers – the largest single risk factor. The germline variants in certain genes like EGFR and STK11 can increase lung cancer susceptibility among never-smokers.

Dr. Zhang says with genetic testing, these variants can be found.

"It turns out that if you have germline variants in the EGFR gene, people have a higher susceptibility to have lung cancer," Dr. Zhang says. "With AI (artificial intelligence) and more in-depth sequencing, we'll be able to find more genetic predispositions."

STK11 (also known as LKB1) is another prominent gene that its germline variants my result in increased susceptibility in many non-smoking lung cancer patients. Germline mutation of this gene can lead to Peutz-Jeghers Syndrome, which leads to the growth of polyps in the gastrointestinal (GI) tract or other parts of the body. It also increases lung cancer susceptibility regardless of environmental exposures.

Current screening guidelines

Low-dose CT scans are available for certain patients, but the current guidelines require you to be at least 50 years of age and have a 20-year smoking history (one pack of cigarettes a day for 20 years, of ½ pack of cigarettes for 40 years). You also need to either be a current smoker or have quit in the last 15 years. 

Dr. Zhang says findings like this argue for expansion of lung cancer screening criteria, especially among Asian females, which is aligned with the findings from FANSS (Female Asian Nonsmoker Screening Study), which screened 1,000 eligible Asian women, ages 40-74. Using low-dose CT (LDCT), the findings showed a lung cancer detection rate of 1.3%. This was higher than a separate study called the National Lung Screening Trial (NLST) which studied high-risk smokers.

Dr. Zhang says that if you have any concerns like lingering cough that lasts for multiple weeks, talk to your primary care provider (PCP). You can get a chest X-Ray to make sure you don't have pneumonia.

You could also have GERD (acid reflux), and these are important to be seen for. If none of the common benign cases are identified, this is where patients should advocate for themselves and ask for a CT scan to check for lung cancer.

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The American Cancer Society (ACS) says other than skin cancer, prostate cancer is the most common cancer in men in the United States.

The good news? Prostate cancer, when caught early, is also one of the easiest to treat.

Salman Syed, MD, a radiation oncologist with OSF HealthCare, describes today’s current treatment options as “exceptional,” noting that most men diagnosed with prostate cancer at an early stage are successfully treated and remain cancer-free after therapy.

The best way to detect prostate cancer early is through screening with a PSA (prostate-specific antigen) test, Dr. Syed explains.

PSA is a protein produced by the prostate that can be measured with a simple blood test. Higher PSA levels may indicate prostate cancer or other prostate conditions. "It correlates with the amount of prostate tissue that you have," Dr. Syed adds.

“In general, we like to see PSA levels below four, but the interpretation depends on a patient’s age and overall risk,” Dr. Syed says. “Some men can develop prostate cancer even with a relatively low PSA, which is why screening decisions should be individualized and discussed with a physician.” 

If you have a strong family history of prostate cancer, you may need to start PSA testing at a younger age. “Current guidelines recommend discussing PSA screening as early as age 40 to 45 for men with higher-risk features, including a family history of prostate cancer, African ancestry or certain inherited genetic mutations.”

Inherited mutations such as BRCA1 or BRCA2 can increase the risk of developing prostate cancer, among other cancers, and can be passed down from parent to child. So, knowing your family history and if you or your parents have genetic mutations is helpful in assessing your cancer risk, Dr. Syed suggests. 

Doctors might also use genomic testing, which analyzes the activity of certain genes within a prostate tumor. These tests help determine how aggressive the cancer is likely to be, allowing physicians to tailor treatment to each patient.

“In some cases, genomic testing helps us safely avoid unnecessary treatments,” Dr. Syed explains. “In others, it tells us when we should treat more aggressively to give the patient the best chance of cure.” 

New and improved ways to diagnose, treat prostate cancer

The OSF HealthCare oncology program has several advanced technologies that help detect prostate cancer earlier and treat it more precisely, often with fewer side effects.

“One of the biggest advances we’ve seen in prostate cancer care is the ability to combine better imaging with more targeted treatments,” Dr. Syed says. “That allows us to detect cancer earlier and personalize treatment, so patients get exactly what they need.”

One example is the multiparametric MRI (mpMRI), an advanced imaging test that provides a highly detailed look at the prostate. This scan can identify suspicious areas that may not be visible on standard imaging, helping doctors detect prostate cancer earlier and guide more targeted biopsies and treatment.

Another breakthrough is PSMA PET/CT, an advanced scan that can detect extremely small amounts of prostate cancer throughout the body. Because it is far more sensitive than traditional imaging, it helps doctors locate recurrent or metastatic disease earlier and plan treatment more accurately. 

OSF HealthCare also offers proton therapy at OSF HealthCare Cancer Institute in Peoria. Proton therapy is an advanced form of radiation that allows physicians to deliver radiation to the tumor while reducing exposure to nearby organs such as the bladder and rectum. 

"With proton therapy, we can often reduce the dose to surrounding healthy tissues compared with conventional radiation," Dr. Syed explains. "That can translate into fewer long-term side effects and better preservation of quality of life for many patients." 

Another highly advanced option available at OSF is high-dose-rate (HDR) brachytherapy, which delivers radiation from inside the prostate.

“HDR brachytherapy is one of the most precise forms of radiation therapy available for prostate cancer,” says Dr. Syed. “Because we deliver radiation from inside the prostate itself, we can sculpt the radiation dose very tightly around the tumor while minimizing exposure to nearby organs like the bladder and rectum. At OSF, this treatment is typically completed in just two sessions, which allows us to deliver a very powerful and focused treatment over a short period of time while maintaining excellent cure rates.” 

Together, these advanced tools allow the OSF oncology team to diagnose prostate cancer earlier, personalize care and deliver highly effective treatment while minimizing side effects. 

Radiation versus surgery: Is there a better option?

In terms of radiation versus surgery, Dr. Syed says they are both highly effective treatment options.

"In terms of cancer control, surgery and radiation have very similar success rates for most patients," says Dr. Syed. "The choice often comes down to differences in side effects and what best fits a patient's lifestyle and priorities."

Rectal irritation, like diarrhea and looser stools during treatment, and other side effects are possible during radiation, but that improves over time, Dr. Syed points out. 

Side effects from surgery include temporary erectile dysfunction (ED), which is regained after surgery. As well as urinary incontinence (accidental urine leakage caused by lack of bladder control), which can tend to last post-surgery as well. Men are encouraged to wear supporting underwear (Depends) to prevent urinary leakage. 

The best starting point is a conversation with your oncology team to discuss what your lifestyle looks like.

If you are actively working and can't have urinary incontinence, radiation will likely be the recommendation. If you have urinary issues already, there are certain radiation options that would be better for you. 

Exercise helps decrease your risk of cancer. Dr. Syed recommends maintaining a healthy weight and staying up to date with your health maintenance and primary care provider, as well as avoiding alcohol and smoking.

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"Anyone that has lungs has a chance of lung cancer,” says Jun Zhang, MD, PhD, vice president of oncology research with OSF HealthCare Cancer Institute.

In fact, 10-20% of lung cancer patients are people who have never even smoked, Dr. Zhang adds. 

"Lung cancer is generally referred to as a 'smoker's disease.' But it turns out now that we're seeing more lung cancer patients without a history of smoking," Dr. Zhang observes. "If we put lung cancer in patients who have never smoked in a separate category, this can be listed as the number five cancer killer in the world." 

This translates to roughly 40,000 Americans every year being diagnosed with lung cancer, despite never smoking cigarettes. 

Women of Asian descent who don't smoke tend to be impacted more by this, Dr. Zhang says, compared to the rest of the population. Research shows that 57% of Asian American women diagnosed with lung cancer have never smoked. Based on this, in a recent study called FANS (Female Asian Never Smoker), researchers at the University of California San Francisco (UCSF), UC Davis and Stanford University are investigating why Asian American women who have never smoked develop lung cancer at unusually high rates compared with other populations.

Sadly, Dr. Zhang says, people who present with lung cancer but have never smoked, are presenting at a later stage. 

"Those patients present to us, at least at my clinic, and they already missed the chance of an early diagnosis. Early symptoms can be cough and shortness of breath, but quite often people are not paying attention to this because they don't smoke and they don't have a chance to get screened," Dr. Zhang says. "That's the sad story, that even though they've never smoked, at the time when they're diagnosed with lung cancer, it's almost always at late stage." 

So, why is this happening? Dr. Zhang discusses five main reasons that non-smokers are getting diagnosed with late-stage lung cancer. The top two culprits will be laid out in this article, with three more to come in part two.

#1: PM2.5 (Particulate Matter)

PM2.5 is the top contributor to non-smokers diagnosed with lung cancer worldwide. The U.S. Environmental Protection Agency (EPA) describes PM2.5 as fine inhalable particles, with diameters that are generally 2.5 micrometers and smaller.

"If you inhale the particles, you cannot get them out of your body. It can get into your lungs, be trapped there, and even get into your circulation and cause problems," Dr. Zhang says. "If we're thinking about cigarette smoking as the number one reason for lung cancer, globally PM2.5 is the second most common reason for lung cancer." 

In the United States, the EPA sets and reviews national air quality standards for PM2.5.

The Upper Midwest region has been below the national average for many years, and according to the EPA, has seen an improvement in air quality since at least 2000. The EPA's national standard is set at 9.0 micrograms per cubic meter. Dr. Zhang says for every 10 microgram per cubic meter increase, it increases lung cancer mortality by 20%.

Some areas in the world can be up to 100 micrograms per cubic meter; Dr. Zhang points out. Vehicle exhaust and industrial emissions along with outdoor fires contribute to these levels. 

The American Cancer Society (ACS) reports lifetime exposure to PM2.5 might increase the risk, and even speed up the onset of various cancers, including lung cancer.

#2: Radon levels in the home

While high PM2.5 levels are the #2 cause of lung cancer worldwide, here in the United States, the second-leading cause of lung cancer (next to smoking) is due to high radon levels. 

According to the ACS, radon is a colorless and odorless radioactive gas. Radioactive elements such as uranium found in soil and rock break down, then move the radon gas from the soil and rock into the air, ground water and surface water.

When radon breaks down in the air, it gives off radiation that can damage DNA in our cells.

“Radon is released by radioactive materials underground, but then they accumulate in the house, especially if it doesn't have good ventilation," Dr. Zhang says. 

The U.S. Centers for Disease Control & Prevention (CDC) says testing for radon in your home is the only way to know if levels are high. It’s recommended to get this testing done before or as soon as you move into the home.

Dr. Zhang says findings like this argue for expansion of lung cancer screening criteria. 

He adds that if you have any concerns like lingering cough that lasts for multiple weeks, especially with shortness of breath, talk to your primary care provider (PCP). You can get a chest X-Ray to make sure you don't have pneumonia.

GERD (acid reflux) and some heart issues could also be a possibility, and these are important to check out. If none of these things exist, this is where patients should advocate for themselves and ask for a CT scan to check for lung cancer that can show if a nodule or mass is present.

To learn more about the Lung Cancer Program at OSF Cancer Institute, or to schedule an appointment, visit the OSF HealthCare website.

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James McGee, MD, MHCM, FACRO, president of the OSF HealthCare Cancer Institute, says those risks can quietly build over time.

"Farmers who are out in the sun all of the time might get skin cancers across the head and neck areas. As they get older and their immune system declines, those become more numerous," Dr. McGee says. "Sometimes that's a prelude to getting a melanoma."

Sun exposure, immunity and cumulative risk

Melanoma risk is influenced by both genetics and sun exposure. That exposure doesn’t always come from a single event. Gradual, day-after-day sun exposure – common in farming and outdoor work – can be just as harmful as intense sun exposure that causes blistering sunburns or sun poisoning.

Repeated skin blistering from sunburn has been linked to the development of more aggressive melanoma later in life. As people age, natural changes in immune function can make it harder for the body to recognize and repair damaged cells, increasing cancer risk.

Occupational patterns also matter. For example, truck drivers who spend years with one arm exposed to the sun through a window may face a higher risk of melanoma on that consistently exposed side compared to the other.

New research links agriculture and melanoma risk

Recent research adds an important environmental and agricultural layer to the melanoma conversation. After analyzing five years of cancer registry data researchers identified a cluster of elevated melanoma rates across a 15-county region of south central Pennsylvania, affecting adults over the age of 50. People in that region were significantly more likely to develop melanoma than residents elsewhere in the state.

Importantly, the increased risk was not limited to strictly rural areas. The cluster included both rural and metropolitan counties, suggesting melanoma risk can extend beyond traditionally “outdoor-only” assumptions.

Even after accounting for ultraviolet (UV) radiation levels and socioeconomic factors, two strong patterns emerged: counties with higher amounts of cultivated cropland and counties with greater herbicide use had notably higher melanoma rates. Previous studies referenced by the researchers suggest certain agricultural chemicals may increase sensitivity to sunlight and interfere with immune function or cause DNA damage – all of which may contribute to melanoma development over time.

Understanding melanoma biology and treatment advances

"Melanomas are all related but can have different molecular signatures that are associated with the underlying cause of the melanoma, region of the body and demographic factors," Dr. McGee points out.

Those molecular differences can offer important clues about which treatments may be most effective. One example is BRAF-related melanoma, which involves a specific genetic change within the tumor. Identifying those changes allows care teams to personalize treatment plans.

Melanoma is also categorized by where it starts in the body. Cutaneous melanoma begins in the skin, while mucosal melanomas develop in areas like the mouth or genital tract. Each type behaves differently and may require a different treatment approach.

Imaging, staging and immune response

Diagnosis often begins with a biopsy of a suspicious skin lesion. From there, doctors may evaluate nearby lymph nodes and use advanced imaging – such as PET scans or MRI scans of the brain – to determine if the cancer has spread. This staging process provides a clearer picture of both disease extent and tumor biology.

Genetic testing of various types can be used to predict treatment response, assess the likelihood of spread, or determine increased risk for subsequent cancers, helping guide both treatment and future surveillance.

Radiation, immunotherapy and a changing treatment landscape

Radiation has traditionally been used to treat melanoma that has spread to the brain or bones. However, melanoma cells contain precursor chemicals that help create melanin pigment, which can act as a radioprotective compound. That protection can make standard radiation doses less effective.

Dr. McGee says delivering a larger dose of radiation all at once can overcome that barrier.

"More and more we're seeing that immunotherapy is coming into play for a possible treatment of melanoma. We've known for a long time that melanomas can act weirdly," Dr. McGee points out. "There have been a lot of reports that were thought to be just happenstance of patients treated with radiosurgery for brain metastases for melanoma, who then had other lesions in their body, get better as well. Those weren't radiated."

In some cases, radiation appears to trigger an immune response. Radiation can cause tumor cells to release antigens, signaling the immune system to attack melanoma cells elsewhere in the body. Combining radiation therapy with immunotherapy is an approach increasingly used for melanoma and other skin cancers.

Dr. McGee now commonly uses a single, high-dose radiosurgery approach. He recently treated a patient with 23 brain metastases in one session that lasted about 20 minutes, with strong responses seen across all lesions. Understanding the underlying biology of melanoma has helped improve these outcomes.

Immunotherapy and survival trends

Immunotherapy has become a powerful option in melanoma treatment, helping the immune system better recognize and destroy cancer cells. These advances are reflected in national survival trends.

According to the American Cancer Society, melanoma death rates in the United States declined sharply between 2013 and 2022, largely due to treatment improvements.

For 2025, the American Cancer Society estimates:

• Nearly 105,000 new melanoma diagnoses
• More than 8,400 melanoma-related deaths nationwide

Melanoma risk increases with age, with the average diagnosis occurring at 66. However, it remains one of the more common cancers in young adults, particularly young women. Lighter skin tone is a significant risk factor, though melanoma can affect people of all skin colors.

Prevention and the role of primary care

While not all melanoma risk can be eliminated, everyday choices can make a difference. Wearing sunscreen, choosing protective clothing, limiting prolonged sun exposure, moderating alcohol intake and avoiding blistering sunburns can all help reduce risk.

Primary care teams play a key role in prevention and early detection.

"One of our major projects is going to be getting our primary care offices to get equipped with tools to help motivate people to reduce their cancer risk through things that are tolerable for them to do," Dr. McGee says. "This gives them the hope that we can reduce their cancer risks."

Increasingly, computer applications and artificial intelligence (AI) are showing promise to help patients and providers sort out suspicious lesions that need to be prioritized for evaluation vs. lesions that have a lower risk of being cancerous.

For people living and working in rural and agricultural communities, understanding how sun exposure, environmental factors and immune health intersect may be the key to catching melanoma earlier or preventing it altogether.

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When it comes to lowering your risk of cancer, what you add to your plate can make a meaningful difference.

Jeanna Rich, an oncology registered dietitian with OSF Cancer Support Services, says the key is nourishing the body with whole grains, colorful fruits and vegetables, fiber-rich foods and Omega-3s.

As someone who works closely with cancer patients, Rich encourages people to think of food as a daily opportunity to fuel the immune system and support long-term health.

Why fiber matters

Most Americans fall short on fiber; a nutrient vital for good gut bacteria, healthy digestion and lowering the risk of colorectal cancer.

Rich says increasing fiber can be simple. Start by working whole grains into meals: oats, wild rice, flax seed, walnuts, pumpkin seeds and chia seeds. They can easily be sprinkled onto cottage cheese, Greek yogurt or oatmeal to boost texture and nutrition.

Research backs up these benefits. A large group of researchers from 15 international cohort studies, including scientists from the American Cancer Society (ACS), analyzed data from more than 842,000 men across North America, Europe, Australia and Asia. Their findings suggest that dietary fiber may lower the risk of developing advanced and aggressive forms of prostate cancer. Additional ACS findings note that whole grains may help fight against advanced prostate cancer.

Rich offers a practical approach to building a fiber-forward breakfast.

"Another great way to add fiber is with our yogurt. A lot of us make yogurt parfaits, but here's a way to take it to the next level. Add chia seeds, flax seeds, pumpkin seeds and walnuts," Rich says. "Top them with berries, which contain a ton of fiber."

Berries – whether fresh or frozen – are packed with vitamins, antioxidants and deep pigments that signal high nutrient content. Rich recommends buying frozen berries and storing them in the fridge to thaw, making them easy to add into yogurt, cottage cheese or morning oatmeal. Frozen produce can be a cost-effective option, especially when items are out of season, Rich says. Thanks to the flash-freezing process, these foods retain their nutrients and offer the same high-quality nutrition as fresh varieties, she adds.

Other high-fiber additions include quinoa, lentils and canned beans, which are paired well with salads, vegetables and hearty meals.

The power of Omega-3s

Omega-3 fatty acids play a crucial role in reducing inflammation and strengthening immune cells.

Some plant-based Omega-3s are found in foods like ground flax seed, but Rich notes that fish-based sources are more efficiently used by the body.

"Some Omega-3s will be found in ground flax seed. However, your body doesn't utilize it as effectively. So, you want to go for those Omega-3s, found in salmon. Keep it frozen in your freezer and choose products that are wild caught. That will have a higher concentration of Omega-3s," Rich says. "Omega-3s help decrease inflammation in our body and increases our fighter cells, so it's a wonderful way to protect from chronic disease and cancer."

Salmon can easily be added into breakfast dishes, salads or purchased as salmon patties. Canned sardines are another convenient, nutrient-dense option.

A need for more vegetables, and more variety

Despite growing awareness of the benefits of produce, Americans still struggle to get enough vegetables into their diet.

"A lot of us are not getting enough vegetables. Many Americans are getting a decent amount of fruit, but vegetables are the tricky ones. When it comes to veggies, diversity is key," Rich says. "On average, most of us only use the same 10 vegetables in our eating routine."

Rich encourages using easy steamer bags filled with multiple vegetables. These mixes often include an array of colors – a good sign you're getting a wide range of nutrients that help fight cancer and chronic disease.

The benefits of polyphenols

Colorful fruits and vegetables bring another powerful nutrient group: polyphenols.

"Polyphenols, flavonoids and lycopene are some key words you may be hearing. Those are the things that are activated in your body and helping protect you," Rich says. "Polyphenols are becoming very popular and are in studies about the gut microbiome. That is considered a source of prebiotics, as well. All these different colors can help feed that good bacteria that helps your immune system be healthy."

Lycopene – found in red and orange produce like tomatoes and peppers – is known to help protect against prostate cancer. Cooked tomatoes are especially beneficial because heat increases lycopene concentration.

Rich suggests adding tomatoes into soups, stews and chili to boost cancer-fighting potential.

What kinds of cancer can a healthy diet protect against?

According to Rich, the right dietary patterns can help protect against a wide range of cancers:

• Breast
• Ovarian
• Gynecologic
• Prostate
• Colorectal
• Gastric

Fiber, Omega-3s and polyphenols are particularly powerful against colorectal and gastric cancers.

Additionally, managing weight through a balanced diet can reduce estrogen production in adipose tissue — a factor that increases breast cancer risk.

Fiber, protein, fruits and vegetables help reduce that risk and help us live a healthier life.

Surprising ways to get more protein

Protein also plays a crucial role in prevention and is especially important for those undergoing treatment.

Rich offers several easy, creative ways to boost protein intake:

• Scrambled eggs: Whisk in cottage cheese to make them “extra fluffy and packed with more protein.”
• Greek yogurt: Blend into red tomato sauce or pasta dishes or use it to make spinach artichoke dip.
• Oatmeal: Add kefir to boost protein and probiotics, helping reduce blood sugar spikes and inflammation.

Foods and drinks to limit or avoid

To best support your health, Rich recommends minimizing:

• Ultra-processed foods
• Artificial additives
• Alcohol
• Excess red meats
• Color dyes
• Processed meats

These items contribute to inflammation and can increase the risk of several types of cancer.

To learn more about how cooking and nutrition work together to improve your health, visit the OSF HealthCare Cancer Institute Teaching Kitchen's website. 

Since 1988, Dr. McGee has been known for his steadfast commitment to excellence in clinical care and early detection of cancer throughout central Illinois.

"I welcome my role as president of the OSF Healthcare Cancer Institute as it further facilitates all those involved in our mission to improve health for those living in rural America, and, by our example, others around the world.  The development of the Institute has been driven by the values of the OSF Ministry that provide us with renewed hope and courage to meet every challenge,” says Dr. James McGee, president of OSF HealthCare Cancer Institute. “The spirit of the OSF Ministry helps us in our weakness and causes us to work together for the good. Our people have been chosen by God for this work; they prove it every day.   My role is to support them as caregivers to those we serve."

In this elevated role, Dr. McGee is responsible for driving the core vision of the OSF Cancer Institute: establishing a world-leading cancer program to improve the health of patients and the communities served throughout the OSF Ministry.

“Dr. McGee brings exceptional clinical expertise, visionary leadership, and a deep commitment to prevention and advancing cancer care,” said Kimberly Russo, CEO, Central Region, OSF HealthCare. “His dedication to innovation, research, and compassionate care aligns perfectly with our vision of treating the whole person and delivering world-class, patient-centered care that shapes the future of cancer.”

Under Dr. McGee’s direction, the OSF Cancer Institute significantly exceeded operational and research expectations. His leadership has been instrumental in the expansion of OSF’s advanced high-dose-rate brachytherapy program; implementation of proton therapy; and the successful recruitment of top medical oncology, radiation oncology and research talent.

Some of Dr. McGee’s recent accomplishments include collaborating with the University of Illinois Cancer Center at Urbana, the University of Illinois College of Medicine and Origin Commercial Ventures, which led to the development of the Breakthrough Treatment Center at the OSF Cancer Institute and the BEAT Cancer Research Initiative. 

These efforts bring early phase cancer control and treatment to patients with an emphasis on engineering to advance cancer care. 

Dr. McGee earned his Bachelor of Science from Quincy College and his medical degree from the Stritch School of Medicine at Loyola University in Chicago. He went on to earn a Master of Health Care Management from Harvard School of Public Health in Boston.

Leading the charge for cancer care across the region, OSF HealthCare Cancer Institute in Peoria, Illinois, will be offering two ovarian cancer clinical trials for patients.

Clinical trial #1 | GOG 3115

The first trial, which launched in early September 2025, gives select ovarian cancer patients the option to receive an antibody drug conjugate (ADC) that targets specific cancer cells. OSF Cancer Institute will be a part of a cooperative group trial with the GOG Partners program, including multiple sites across the United States.

Michelle Rowland, MD, a gynecologic oncologist with OSF HealthCare, says it will allow for lower dosing, which is an improvement from traditional chemotherapy. This creates fewer side effects, while still being more effective.

"Recently in patients who have had their ovarian cancer recur, we've noted that we have a new drug called mirvetuximab soravtansine with Carboplatin, which works really well in those patients. This is now a trial looking at using this drug in cancer patients with a new diagnosis," Dr. Rowland explains. “This changes what the standard of care is and hopefully improves the responses we're getting and lessening the side effects of their treatment. This will be for patients who are newly diagnosed with ovarian cancer and require chemotherapy."

Common side effects for chemotherapy patients with ovarian cancer:

• Nausea 
• Fatigue 
• Neuropathy (numbness and tingling in hands and feet)
• Bone pain 

Dr. Rowland says OSF Cancer Institute is currently looking for patients with a new ovarian cancer diagnosis for the upcoming trial.

Any new ovarian cancer patient who has not received chemotherapy before would be eligible to try this new drug. 

Clinical trial #2

A second study, which is a national cooperative group trial, is set to offer new treatments for patients who have already undergone ovarian cancer treatment. This is for patients who did well during the treatment, but their cancer came back. 

"These treatments typically involve some of the antibody drug conjugates, but also immunotherapy and combinations of those medications. This gives patients new options they might not see," Dr. Rowland says. "So, for someone who is seen in our system, or seen elsewhere and wants a different treatment option, that will be open here." 

The second trial is expected to launch in late 2025, as OSF HealthCare plans to open additional trials for patients.

Ovarian cancer common facts

For a long time, ovarian cancer has been called the "silent killer." Dr. Rowland wants to dispel that myth, because there are signs and symptoms to look out for, she says. 

Ovarian cancer symptoms:

• Abdominal bloating
• Changes in bowel habits, such as constipation
• Pelvic or abdominal pain
• Lack of appetite
• Feeling full after a few bites of food
• Constantly feeling the need to urinate

"Those are the most common and can be related to a lot of different things. So, if you're having these symptoms, we encourage patients to reach out to their doctor,” Dr. Rowland says.

For breast cancer patients, to be eligible for genetic testing, there are a few guidelines people need to meet. For ovarian cancer, all it takes to receive genetic testing is to have the disease. This is because a larger number of ovarian cancer patients will have a genetic mutation, roughly 15-20%, Dr. Rowland says. 

Robotic-assisted surgeries are an option for select surgeries at OSF HealthCare. Surgeons can use the brand-new da Vinci 5 robotic system by Intuitive. Dr. Rowland says she has seen a benefit for ovarian cancer patients since using the new technology. 

An ovarian cancer survivor group is having a walk at the OSF Cancer Institute on Saturday, September 20. This gives a way for people to support ovarian cancer survivors and learn more about the disease. More information about the 2025 Teal Butterfly Blessings Ovarian Cancer Awareness Walk can be found here.

For more information about gynecologic cancer services and resources at OSF, visit the OSF HealthCare website.

Video Interview Clips

While this seems straightforward, this isn’t a quantity vs. quality scenario. It’s a mix of both, personalized to everyone in different ways.

A late-phase trial published in the New England Journal of Medicine finds people who follow an exercise program after undergoing surgery and chemotherapy can reduce the risk of cancer recurrence, a new cancer diagnosis or death by 28%. The findings were presented on June 1 at the annual meeting of the American Society of Clinical Oncology (ASCO), focusing on those who had Stage 3 or high-risk Stage 2 colon cancer.

Nathaniel Leman is an exercise physiologist with OSF HealthCare. He works alongside patients with cancer, mapping out plans to keep them exercising, despite a cancer diagnosis.

Exercise is helpful to patients with cancer

During a cancer journey, exercise helps deliver medication through the body as it's intended, because a person's blood vessels are opening, allowing the drugs to get to the areas impacted by cancer better. 

"We know exercise is so beneficial for our bodies. Specifically for patients with cancer who deal with a lot of fatigue, tiredness and low energy," Leman says. "They also deal with a lot of joint and muscle pain, maybe even bone pain. Most of the time they have weakened immune systems as well. There's a lot of things through their treatment journey they'll deal with; weight loss is another one."

How exercise is beneficial for patients with cancer

"Exercising with cardio and strength training is really good for our hearts, lungs, muscles and joints. The benefits also include our mental health, and it helps keep our weight consistent," Leman adds. "It also helps to boost our immune system and keep us healthy for a long time."

Leman and his colleagues rely on recommendations from the American College of Sports Medicine (ACSM) to put together plans for patients with cancer. That includes 150 minutes of moderate, cardiovascular or aerobic (using body’s main muscle groups in repeated motions) exercise per week. This can break down into 30 minutes of exercise, five days a week.

If 30 minutes at one time is too much for a person, feel free to break it down into two 15-minute exercise periods, sprinkled throughout your day. Even three 10-minute periods are beneficial.

The main goal is to just get people to start moving. 

How to start moving

"That includes anything from walking to an aerobic bike on a moderate setting," Leman says. "Walking in a pool and doing light jogs inside the pool is something where we can take that pressure of gravity off."

If people want to achieve vigorous exercise, Lehman recommends 75 minutes a week because of the added pressure that's put on muscles and bones. 

If strength training is more your speed, Lehman recommends two to three days a week. This can include light squats, shoulder press, bicep curls, triceps extensions and rows as a few examples. Make sure to have a day of rest in between. 

Avoid powerlifting during cancer

Power lifting (power clean, heavy squats, deadlift) or exerting too much energy during a cancer journey is something to avoid, Lehman recommends. 

"We don't want to do that type of workout where we're over stressing our body to a point we can't move the next day," Lehman says. "Those athletes train for years and years and years, and they put a lot of fatigue on their body that our patients with cancer just can't handle." 

Marathons, triathlons, Iron Mans and Spartan races should be avoided as well. These extremely tough exercise events would cause too much stress on the bodies of patients with cancer. 

Lehman says exercise is good at lowering the risk of cancer, but it doesn't outright prevent cancer. 

Lehman says there is a difference between an active lifestyle and exercising. A basic active lifestyle can include things like daily chores around the house, but he wants patients to take things a step further and add committed time to exercise specifically. However, if a person is working outside in the yard all day, that can be a great amount of physical activity which could supplement exercise on that specific day.

The European Society of Cardiology reports a sedentary lifestyle for two decades is linked to being two times at risk of premature death, compared to being physically active. The American College of Sports Medicine recommends 8,000 steps a day and says that for every 1,000 added steps per day in people with a sedentary lifestyle, reduces the risk of heart disease and death by 15 percent.

OSF HealthCare exercise physiologists offer a free exercise consultation to get started. Contact your oncology care team here to learn more about exercise plans during cancer.

Video Interview Clips

The Peoria, Illinois-based hospital system has brought surgical oncologist Tamara Floyd, MD, to the care team at OSF HealthCare Saint Francis Medical Center in Peoria. Dr. Floyd performs cytoreductive and HIPEC (hyperthermic intraperitoneal chemotherapy) surgeries in Peoria, while also seeing patients in Bloomington and Galesburg.

HIPEC procedures are mostly for patients who have tumors or cancer spread in the abdominal cavity. 

Cancerous tumors are removed through cytoreductive surgery where the surgeon initially attempts to remove as much of the cancer as possible. Surgery is then followed by HIPEC, which is when a heated chemotherapy – at just over 106 degrees Fahrenheit – is administered into the abdomen. The heated chemo is then circulated around the area inside the abdomen to treat any remaining microscopic tumor cells.

HIPEC can be beneficial for several types of cancer patients. The one it benefits the most is LAMN, or low-grade appendiceal mucinous neoplasm. HIPEC is considered a standard of care for patients who have seen their cancer spread into the space in the abdomen that contains the abdominal organs.

These can be appendix, colorectal, and now more data indicates stomach cancer patients may benefit from HIPEC, Dr. Floyd says.

"Additionally with more data, pancreatic cancer is being looked at as well. Even patients with breast cancer. Another cancer that benefits from HIPEC is peritoneal mesothelioma." 

HIPEC can be a viable treatment option at any stage, Dr. Floyd says. But as some people are diagnosed with later stage disease, it can feel like no options are possible. HIPEC changes that.

"It's beneficial to have the option of doing HIPEC, or cytoreductive surgeries, for patients who have peritoneal spread of disease, which for most cancers means it is a stage 4 disease," Dr. Floyd says. "In a lot of instances, if you're talking about stage 4 disease, there aren't a lot of other options."

While HIPEC is a viable option for low-grade cancers, it's also a helpful option for later stage, more aggressive cancers. Patients with signet ring or goblet cell features, which are more aggressive subtypes, can also be treated with HIPEC. 

"Signet ring is one of the subtypes of appendiceal, colon or rectal that can be treated. There are even some subtypes of gastric or stomach cancer that are considered a signet ring or have signet ring features," Dr. Floyd says. "Cytoreductive and HIPEC can be considered for those patients."

Throughout a cancer journey, combining traditional chemotherapy that is administered through IV with HIPEC provides a "synergistic effect" Dr. Floyd says. HIPEC allows the chemotherapy to be administered directly to the cancer cells and kill them that way. 

Dr. Floyd has done one HIPEC at OSF Saint Francis so far and has another planned soon. It's anticipated that within the next year, Dr. Floyd and her team will start to do three to four HIPEC surgeries a month as OSF HealthCare Cancer Institute continues to grow as a destination center.

Patient recovery times can be one to two weeks in the hospital after HIPEC surgery, which is why having this option for Central Illinois patients is so important. It allows the patient and their families to stay close to home, instead of having to travel hours away. Dr. Floyd says the longer travel times can turn patients and their families away from pursuing care. 

Heated chemotherapy can also be used in thoracic cavities. This would then be called HITEC or HITOC, Heated IntraThoracic Chemotherapy. This is for patients who have disease spreading in the pulmonary area. 

Types of cancers that can be treated by HIPEC: 

-          LAMN (Low-grade appendiceal mucinous neoplasm)

-          Appendiceal

-          Colon

-          Rectal

-          Gastric

-          Stomach

-          Pancreatic

-          Breast

-          Mesothelioma

-          Ovarian

For more information on cancer treatment options at OSF, visit the OSF HealthCare Cancer Institute website.

Video Interview Clips

A colonoscopy at age 15

But why? Those at an average risk of colorectal cancer are recommended to start getting colonoscopies once every ten years, starting at 45 years of age.

"My dad was diagnosed after just turning 26. Because it was colon cancer, they recommended I be seen ten years before. The doctors said when I turned 15 to get a colonoscopy," Jaxson says. He was just a baby when his father passed away.

Jaxson’s father, Michael, was an avid runner in great shape. Angie Brown, Michael’s wife and Jaxson’s mother, says Michael had no family history of colon cancer, and never drank or smoked. At the age of 26, Michael was diagnosed with stage 3 colon cancer. He underwent six months of chemotherapy and was in remission for almost four years. In 2013, Michael was diagnosed with a rare form of stage 4 colon cancer called signet ring cell adenocarcinoma.

“If he can do it, I can do it!”

Angie says for years, she has helped prepare her sons to know the importance of cancer screening, and that they’d have to undergo a colonoscopy from a young age.

“He figured that if he could go out there and show people that a 15-year-old boy is willing to go through a colonoscopy, without having any symptoms, then anybody can do it,” Angie says. “We had a good amount of people who sent messages and said, ‘if he can do it, I can do it!’”

Jaxson says it helped to know from a young age that the day was coming. Afterwards, he said it “wasn’t that bad.”

"They have you roll over on your side, then they inject the stuff in, and it works like a charm. You're out and don't remember a thing. Best sleep you'll ever get," Jaxson laughs. 

Jaxson’s bravery can inspire others

Daniel Martin, MD, a gastroenterologist with OSF HealthCare, oversaw Jaxson’s treatment. He says Jaxson’s bravery to undergo something uncomfortable, yet potentially lifesaving, should be inspiration for everyone.

"Colon cancer, if caught early (even if not caught at a polyp stage), is a very treatable condition. Where in the early stages of disease, greater than 90% of those patients are going to be disease free at five years," Dr. Martin says. "One of the advantages of colorectal cancer screening is that we can prevent the disease. With colorectal cancer, in a colonoscopy, you can identify the precursor lesions called polyps and remove them during the exam."

Colon cancer is the third-most diagnosed form of cancer in both men and women.

“Lung is first for both, breast cancer is second for women, then colorectal cancer is third. For men, prostate is second, colorectal cancer is third. Colon cancer is the second-leading cause of cancer mortality in this country,” Dr. Martin explains.

The prevalence of colon cancer, along with the rareness of Michael’s signet ring colon cancer, led Angie and Michael to launch the Michael P. Brown Colon Cancer Foundation which lives by the motto “Get Busy Living.”

“A lot of people think you’re guaranteed a long life, especially if they’ve had parents who lived into their 80s and 90s,” Angie says. “You just never know what’s going to happen. If you have a bucket list, start doing those things. Don’t wait until you’re retired.”

The Foundation hosts Michael’s 5K Run for Life each year, raising money for signet ring research

“We try to be an outlet for people to get information about signet ring colon cancer. My husband used to field most of those calls, but now I do. My boys are getting involved too,” Angie says. “If there’s a parent who has cancer, they’re willing to talk to kids about that.”

Signs and symptoms of colon cancer

"The most common concern would be bleeding in your stool. But that would also include abdominal pain that's new or different," Dr. Martin says. "Or changes in the frequency or caliber of your stools."

This was mainly the case with Michael, Angie says.

“Initially, my husband’s symptom was belly pain. He was put on a couple of different medications because it was thought to be a stomach ulcer,” Angie says. “It didn’t work. He started having constipation, diarrhea and vomiting. We went into the emergency department, and he got the diagnosis of colon cancer.”

Traditionally, colon cancer is seen in people in their 60s and 70s. However, more younger people are starting to be diagnosed with colon cancer, Dr. Martin says.

"Specific to colorectal cancer, there are various options available now for screening. We recommend procedural screening with colonoscopy whenever possible. But with the advent of stool studies that are readily available and have been covered by insurance, that has helped increase the pool of patients who are receiving appropriate screening," Dr. Martin says. These readily available options are so important, Dr. Martin says, because most colon cancer patients are getting diagnosed at a later stage in the disease.

In the past, things like smoking, obesity and unhealthy lifestyle choices have been thought to cause colon cancer. Dr. Martin says in addition to that, more recent studies have shown processed foods to be a concern as well, adding that our gut's microbiome may show early indicators of cancer. A study done by Harvard Medical School investigators found that certain types of gut bacteria could lead to the development of precancerous colon polyps. 

Dr. Martin credits the OSF HealthCare cancer tumor boards and medical teams for creating a more organized process over the last five to 10 years that takes care of patients from diagnosis to treatment. 

Jaxson says now that it’s all said and done, the colonoscopy process was not as bad as most people think. This is on par with what most patients say, Dr. Martin adds. His word of caution? Many of his patients undergoing a colon cancer diagnosis wish they would have gotten colonoscopies earlier on.

To schedule a screening, speak with your primary care provider first and get a referral. You can find more information about colonoscopies on the OSF HealthCare website.

Jaxson Brown Video Interview Clips

Angie Brown Video Interview Clips

Dr. Daniel Martin Video Interview Clips

Innovative Technologies at the Forefront

Leading-edge cancer treatments like proton beam therapy, brachytherapy, genetic counseling and dietetics are all offered within the OSF Cancer Institute, providing patients with a one-stop-shop during their cancer journey.  

Proton therapy

Proton therapy was first offered on April 1, 2024.

"Proton therapy lets us offer radiation therapy to patients that maybe wouldn't have been able to tolerate side effects due to tumor location, or factors such as prior radiation treatment to the same area," says Tom Cox, the vice president of operations at OSF Cancer Institute. " This is possible because protons stop after passing through a tumor, eliminating the radiation effects on tissue often treated incidentally to photon (X-ray) therapy. The OSF Cancer Institute is on track to have treated 180 patients by April 1, 2025 – which far exceeded the original first-year target of 130 patients.

Brachytherapy

The brachytherapy suite offers a more patient-friendly way for mostly prostate and gynecological (cervical, endometrial) cancer patients to receive treatment. This option involves placement of applicators or needles directly into tumors so that very controlled, effective radiation can be delivered in discrete volumes. Since the radiation is delivered from within the tumor, there is a dramatic reduction of the dose to normal tissue, even those near the tumor itself. The dose is delivered with high-dose rate techniques so the therapy is delivered in just a few minutes time.

"Being able to bring the introduction of the applicators into the body, the treatment planning CT and the treatment all in one room, has created a much better experience. We're having some really good outcomes there, and we think we can expand what we're able to do there,” Cox says.

Intuitive Ion robot 

The OSF Cancer Institute’s pulmonology team offers state-of-the-art diagnostic tools and treatments, including minimally invasive, robotic surgeries and robotic assistive bronchoscopy. This includes the Intuitive Ion Robot, which allows care teams to get early answers and advance care for lung cancer patients.

"We're going to leverage the ability of an ion robot in the interventional pulmonary lab to really upend how we do the front end of lung cancer care," Cox says. "That robot is going to enable us to biopsy smaller lesions. It has fewer side effects than when you're getting a lung biopsy that's CT-guided. You can also do a staged EBUS (endobronchial ultrasound) exam, so you can diagnosis and stage at the same time."

Rachael Davis, MD, a pulmonologist at OSF Cancer Institute, and her team have been using the ion robot weekly. Dr. Davis and her team are training more providers, and by this summer they’re expecting to quadruple – or more – how often it’s used. 

HIPEC procedures

Hyperthermic intraperitoneal chemotherapy (HIPEC) surgeries are now offered at the OSF Cancer Institute. Tamara Floyd, MD, a surgical oncologist with OSF performs the open surgery and removes tumors from the abdomen. In the HIPEC procedure, heated chemotherapy is circulated through the body for a period of time. The first case went extremely well, and Dr. Floyd is planning her second case for mid-March. 

In addition to treatment options, the OSF Cancer Institute is increasing cancer supportive services in the Peoria region as well.

• Cancer navigation - 13% increase (Specially trained OSF Mission Partners walking you through the process of cancer care) 
• Dietetics - 64% increase
• Palliative medicine - 213% increase (Helps control symptoms, augments treatment from physicians) 
• Genetic counseling - 20% increase

Nutrition journey during cancer

Part of the dietary benefits OSF Cancer Institute offers is in the CEFCU Teaching Kitchen. Oncology dietitians work with patients on recipes to cook and are there with them step-by-step during their cancer journeys. Cox says 50% of people who come in for cancer treatment have dietary risks, while 80% of those people suffer malnutrition during treatment. Having a trained, professional dietary team walking alongside you helps fight those negative complications.

OSF Cancer Institute Culture

Cox credits the Institute’s first-year success to the culture of those who work there. The goal, he says, is to offer cancer support services across the entire spectrum of life. 

"The Mission Partners that work in this building have completely bought in to the idea that we all are advocates for cancer patients. We're always asking patients what they need, to see if we can help them," Cox says. "If we hear there's an issue with travel, or they're having trouble keeping food down, or if their children are not coping very well (with a loved one's cancer diagnosis), we know there are resources in the building, and we try very hard to line up those resources. You can feel it when you walk through the building."

Support services after cancer treatment 

"We can get you with a nurse, an exercise specialist and a dietitian to get back to your best life after cancer. Maybe you like to run a lot and ran half marathons, and you think you'll never be able to do it again. We have rehab and exercise specialists here and nutritionists. Who says you can't do that again? We're going to work with you to see you can get to the life after cancer you want to get to,” Cox says.

Services and medical professionals continue to grow

Building off the first year of OSF Cancer Institute, the administrative team continues to hire world-class medical professionals to offer cancer care in Peoria. A breast surgeon was recently brought onto the team, and a colorectal surgeon will be starting soon.

Additionally, the fourth floor of the building will be built out soon. Cox says this will give much-needed space for the surgical oncology and medical research teams. Research-focused medical oncologists are currently being recruited as well.

Leaving OSF Cancer Institute healthier, and more aware

Patients who leave OSF Cancer Institute don't just leave the building as healthier people; their awareness continues and will benefit other people. Cox admits a cancer diagnosis is not an easy thing to go through, and that the support from the OSF care team doesn’t stop when you walk out the door.

Grateful for community support

Cox says he’s been humbled throughout the years of working in oncology by the incredible commitment of the community and region to the OSF Cancer Institute.

"It is overwhelming to me, the philanthropic spirit of our community and extended community," Cox says. "I take that as, they've made a big commitment to us, and we're making a big commitment back. We're going to bring things to central Illinois that have not been here before. We are going to support you and your family members throughout your life and keep you as healthy, relative to cancer, as we possibly can."

Looking to the future

Cox says the OSF Cancer Institute is looking to bring more pediatric cancer support services to the building, the work collaboratively alongside the adult services.

The team is creating both a lung lesion clinic and a lung multidisciplinary clinic, which aims to reduce the time from finding a cancerous lesion to treatment. The lesion clinic is expected to open in late spring.

The OSF Cancer Institute intake team has been created with oncology nurses who will answer patients’ questions on the very same day, to see if services are right for you.

Cox adds that OSF is planning to put together an early detection hotline as a resource for the community to know if or when they should be screened for cancer.

To learn more about the OSF HealthCare Cancer Institute, visit its website to view the services offered and find contact information to get connected.

Video Interview Clips

As we begin a new year at OSF HealthCare, we’re reflecting on 2024 and the major strides in digital transformation to make access to care and health information seamless for our patients. At OSF, we continue to collaborate with our academic and business partners to leverage collective expertise and to responsibly use the power of artificial intelligence, always taking care to use guiding principles of what is fair, appropriate, valid, effective and safe (FAVES).

The efforts are highlighted here in our Top 10 Digital Health and Innovation stories of 2024 in no particular order.

1. OSF Unveils new 55+ primary care service in south suburban Chicago: Called OSF Complete Care 55+, this is a unique collaboration between OSF HealthCare Little Company of Mary Medical Center and OSF OnCall, the digital arm of the health care Ministry. When launched in early 2025, this primary care program will incorporate in-person visits, plus a mix of virtual care, digital health monitoring tools and 24/7 access to a care team focusing on those with chronic conditions.

2. Building an AI prepared workforce: OSF HealthCare leaders took just six weeks to develop mandatory training about generative AI for all 24,000 OSF Mission Partners (employees) because tools were already publicly available. Melissa Knuth, Vice President of Planning, outlines that to rise to the challenge, she worked with OSF Innovation to use mixed media to keep the content interesting and tapped generative AI tools to assist with the content creation.

3. OSF Digital Hospital patients in Rockford area say it’s the best medicine: OSF OnCall expands its digital hospital program to Rockford and receives rave reviews from some of its first patients. In addition, a well-known farm broadcaster shares her story about receiving acute-level care from the comfort of her own home and urges others who are eligible to consider the option.

4. OSF Innovation sets the table for solution to prevent cancelled surgeries: Two OSF HealthCare nurses turned to the OSF Innovation Studio team to help improve their Device Table software that serves as a database for implanted medical devices – offering information needed for surgical teams to reference for safety in surgery planning. We also reported on the creation of a spin-off company, OpenSurg, which will license and promote widespread sales of Device Table and related support features.

5. OSF HealthCare experts: ‘Establish guiding principles when developing digital care strategy’: OSF OnCall was a spotlight vendor and presenter at this year’s American Telemedicine Association’s annual Nexus conference in Phoenix, Arizona. OSF OnCall Senior Vice President Jennifer Junis advised during her presentation that health systems use guiding principles when developing their approach to digital health and to involve clinicians and patients when piloting new programs and digital tools. OSF HealthCare has also become a founding member of an ATA Digital Center of Excellence.

6. Mapping the future for early diagnosis of rare diseases: A Jump ARCHES grant-funded project with the University of Illinois Urbana-Champaign is using generative AI and knowledge graphs that map symptoms to detect rare diseases. Adam Cross, MD, who leads the OSF Children's Innovation Lab in Peoria, Illinois, wants to create a point-of-care tool for primary care providers to help patients get an early diagnosis of a rare disease.

7. Health economist: Connectivity and trust can expand telehealth: OSF OnCall hosted its first-ever digital health symposium which drew nearly 150 clinicians and vendors. Keynote speaker health economist and advisor Jane Sarasohn-Kahn stressed evidence-based digital technologies can improve health outcomes, but health systems need to build trust and expand community partnerships to increase engagements.

8. Fast-Tracking Hope: Rapid Intake at the OSF Cancer Institute: OSF HealthCare began 2024 with the opening of its new comprehensive Cancer Institute, offering advanced radiation therapy such as brachytherapy and proton beam therapy.  It also launched a new rapid intake system, developed by OSF OnCall and OSF Innovation to offer a single point of contact through OSF-HOPE (844- 673-4467) so cancer patients can be immediately connected to treatment and support services.

9. Piloting a smarter colonoscopy: OSF HealthCare St. Joseph Medical Center piloted artificial intelligence-backed colonoscopies, using a company called GI Genius, to improve detection of precancerous polyps. During the pilot, the adenoma detection rate (ADR) averages increased among all patients involved to as high as 12%, while individual physician ADR increased as high as 32.8%. The technology is now being implemented across the OSF Ministry.

10. Testing the path to better concussion diagnosis: An OSF Innovation lab-designed FlightPath app is now being tested by athletes at Illinois State, Bradley and Illinois Wesleyan Universities. The app only takes about two minutes to collect more than a million data points as a person tries to catch a hummingbird within a 3D space on a screen. The clinical trial could last two years. 

The official blessing of the OSF HealthCare Cancer Institute, located on the campus of OSF HealthCare Saint Francis Medical Center in Peoria, was conducted by the Most Rev. Louis Tylka, Bishop of the Peoria Diocese on Tuesday, February 13.

The OSF Cancer Institute will be a one-stop destination for a patient’s cancer journey.

"The greatest difference that will happen in this building in comparison to many other centers, is that we've brought everything together. All of the therapies with the clinicians, together with support services and survivorship, together with the kitchen and nutrition," says Robert Sehring, CEO of OSF HealthCare. "It's the ability to bring all of those pieces together and have people collaborate. Whether it's a tumor board, working through a diagnosis or treatment plan. We're doing all of that to meet the needs of the patients that are going to come here.”

One of the new treatments happening inside the OSF Cancer Institute is proton beam therapy. This will be the only center outside of Chicago and St. Louis offering proton therapy in the region. Dr. James McGee, founding director of the OSF HealthCare Cancer Institute, says this treatment is less invasive than current treatments being offered.

“It's where a packet of energy with positively charged proton particles is used to go to one spot of the tumor and treat that spot of the tumor,” Dr. McGee says. “We're able to go anywhere in the tumor. Very little dose on the entry side, and no dose on the exit side. Using all of that, we can corral the radiation into the tumor and reduce the dose of radiation to the normal and healthy tissues that we don't want to get incidental radiation, like the lymph nodes and things where the immune response is being mounted to that cancer."

The proton beam therapy is powered by a Varian ProBeam® 360° System cyclotron. Dr. McGee says the ability to rotate the System 360° allows the technology to target cancer from any angle.

 "We know the biological effect of protons is often felt to be at least 10% higher than with X-ray therapy. That gets factored into treatment planning. We also know the ability to give these treatments in a way that doesn't affect the immune system, allows the actual radiation treatment to be more effective,” Dr. McGee says. “We're seeing more and more evidence that there is better tumor control in certain situations. People are not failing that would've failed at those doses with X-ray therapy. Also, we're not generating secondary cancers from the radiation."

The first patients are expected to be seen by the end of the month. It is estimated the OSF Cancer Institute will treat upwards of 3,700 cancer patients annually with an estimated economic impact on the Peoria-area of $1-billion over the next decade.

Other key features for patients include:

- Brachytherapy: Also known as implant radiation, is a treatment that is delivered from inside the tumor and can deliver more intense doses of radiation at the tumor site. Brachytherapy is most commonly used to treat cancers of the female pelvis, prostate, breast, eye and skin. Currently, patients are transported all over the hospital in order to receive these procedures. When the HDR Brachytherapy suite in the OSF Cancer Institute opens, everything will happen here. This state-of-the-art surgical suite is outfitted with a GE C-T on rails, specially designed for this space. This will make for a much better patient experience. 

 

- Teaching Kitchen: The CEFCU Teaching Kitchen will offer a healthy lifestyle educational environment by focusing on prevention and wellness efforts to lower the risk for cancer and cancer recurrence. Patients and families affected by cancer will benefit from classes where they learn how to prepare foods that address specialized needs while going through cancer treatment. Prevention of other diseases and chronic health conditions will also be addressed, with advanced IT technology offering remote access to facilitate live-streamed classes. 

 

- Healing Garden: Located on the east side of the campus, this area has a number of features including statues of the Welcoming Virgin Mary, St. Peregrine, the patron saint of cancer, and St. Francis of Assisi. There is a water feature along the path, and the space will host the Gilmore Foundation Teaching Garden. The fresh food grown here will be used in the teaching kitchen, which is right next to the healing garden.

 

- Cancer Support Services: The main focus is assisting patients and their families from diagnosis through survivorship, as well as prevention and for those at a higher risk of developing cancer. These services include nurse navigation, dietitians, financial navigation, counseling, cancer specific clinics and survivorship. 

Photos from OSF HealthCare Institute Blessing

Robert Sehring Video Interview Clips

Dr. James McGee Video Interview Clips

OSF HealthCare Cancer Institute B-Roll

A cancer diagnosis can be overwhelming. Nurse navigators offer much-needed service and support to help prevent patients from becoming overwhelmed by uncertainty, appointments, diagnostics, treatment, their job, and financial concerns, as well as the psychological impact of a serious diagnosis. Cancer patient navigators provide education, advocacy and support while facilitating the process of cancer care.

But the job of a cancer patient navigator can be challenging. The complexities of health care, the gravity of a cancer diagnosis, and the growing number of cancer patients served by the health system can create enormous stresses on all involved, including the cancer patient navigators. This can lead to burnout which could threaten the ability to recruit and retain those performing this critical service for cancer patients. OSF HealthCare has 15 cancer patient navigators at its largest hospital, Saint Francis Medical Center in Peoria, Illinois. Each navigator specializes in serving patients with specific types of cancer.

At any point in time, one navigator in a specialty might have much more work than others in the same specialty. However, OSF cancer patient navigators typically do not transfer care to another navigator when workloads are heavy, because they seek to maintain consistent patient relationships throughout the care journey. Within these constraints, a team led by OSF’s Senior Fellow for Innovation, Jonathan Handler, MD, sought to develop a solution to better balance workloads among cancer patient navigators within a cancer specialty.

The team included researchers from OSF Healthcare and its OSF Innovation group, the University of Illinois College of Medicine Peoria, the University of Illinois Urbana-Champaign, and the Northwestern University Feinberg School of Medicine. The work was funded by a grant from Jump ARCHES, a strategic partnership between OSF HealthCare, the University of Illinois College of Medicine at Peoria, and the University of Illinois Urbana-Champaign.

The team developed a model to predict the upcoming week’s work for each navigator’s existing patients and for new patients needing navigation. A second model then distributes the new patients among navigators within a specialty to minimize differences among those navigators in their upcoming week’s workload. The model makes the predictions using data already contained in a patient’s electronic health records, such as demographics, cancer type, and prior health care utilization.  

As part of this research, predictor-informed distribution and random distribution were compared, assessing resulting workload differences among navigators in the same cancer specialty. The random comparison was used because OSF cancer patient navigators distribute patients nearly-randomly; except in unusual cases, patients are distributed to relevant specialized navigators on an alternating basis. Anticipated patient needs, navigator experience, and existing workload are generally not considered for this distribution. In this retrospective simulation study, the predictor-informed model achieved significantly greater workload fairness than random distribution. This research was published in JCOâ Clinical Cancer Informatics, a peer-reviewed scientific journal.

“At OSF HealthCare, we use innovation to create greater effectiveness, efficiency and access for patients who want clinical excellence, convenience, support, and a positive patient experience,” Dr. Handler explains. “We also take innovative approaches to retain our greatest asset, our Mission Partners (employees), and to help ensure that OSF HealthCare remains an outstanding and gratifying place to work.”

To integrate the smart algorithm for improved cancer patient navigation, OSF Innovation plans to leverage OSF Community Connect, a platform that automates workflows to help OSF Healthcare orchestrate care and resources.

Tenille Oderwald, MSN, RN, a co-author of the paper and manager of Oncology Services at OSF Saint Francis, says the next step will be to pilot the tool. With the planned opening of the OSF Cancer Institute next year, Oderwald says being able to help navigators’ support and guide patients through appointments and treatment will be important as more people seek care through OSF at its world-class facility.