Top 5 Digital Health stories of 2025

Digital health continues to reshape how people connect with care — breaking down barriers of distance, time and access in ways that were once unimaginable. In 2025, those advances moved from promise to practice, with new technologies helping patients get care faster and using data to make more informed decisions. OSF HealthCare, through its OSF OnCall digital health arm, has been able to reach communities that have long been underserved. From artificial intelligence and virtual care to immersive technologies and smarter data use, OSF OnCall continued to push health care forward.

These are the Top 5 digital health stories of 2025, in no particular order.

From crisis to confidence: Patient praises new OSF 24/7 primary care – Marci Schneider Batsakis of Orland Park, Illinois was the first patient enrolled in OSF CompleteCare 55+, a new hybrid model of primary care in Evergreen Park, using virtual visits and digital connections to help older people get fast access to providers and stay on top of their health. Schneider Batsakis called the round-the-clock care team number when her blood pressure became dangerously high and that led to timely treatment in the hospital, follow-up support, and a care plan tailored to her needs.

OSF HealthCare receives $1.5 million for new mobile pregnancy and postpartum care unit An OSF OnCall Connect mobile van will offer doorstep service as an extension for women on Medicaid enrolled in a pregnancy and postpartum digital support program. Meridian and Centene Foundation provided $1.5 million in funding for the van to operate in maternity deserts in 12 Illinois counties.

OSF HealthCare offers another layer of monitoring for moms and babies – OSF HealthCare launched 24/7 virtual labor monitoring to enhance in-person care with AI technology. AI software alerts OSF OnCall Acute OB nurses to potential risks, enabling quick coordination with staff at Family Birthing Centers at hospitals across the OSF HealthCare Ministry. This is part of a broader effort to reduce mortality rates among women and babies which remain high compared to other wealthy nations. As part of that effort, we also opted to extend to all patients in the I-80 region, regardless of payor, a Medicaid program for virtual visits and digital support. The area has lost a number of OBGYN providers.

Skip the wait with new OSF OnCall virtual exam visit – OSF OnCall Urgent Care walk-in clinics can get busy, especially during the winter with respiratory viruses. So OSF HealthCare installed new technology in urgent care clinics, allowing patients to do in-office virtual visits and bypass the waiting room. Visitors to the OSF OnCall Urgent Care can get accurate testing and diagnoses using digital tools and an on-screen OSF medical provider.

OSF HealthCare using virtual ER to cut patient wait times – OSF HealthCare is using an innovative approach to help reduce wait times in the emergency departments at OSF HealthCare Saint Elizabeth Medical Center in Ottawa and Peru. Patients who meet certain criteria will be given the option to divert to a virtual medical exam through the use of advanced technology and an onsite nurse.

Top 5 OSF Innovation stories of 2025

As we kick off a new year at OSF HealthCare, we’re looking back at 2025 and the big steps we took to make it easier for patients to access care and health information. Working alongside our academic and business partners, we continued to tap into shared expertise and use artificial intelligence in thoughtful, responsible ways — always guided by what’s fair, appropriate, valid, effective and safe (FAVES).

Those efforts are reflected in our Top 5 OSF Innovation stories of 2025, listed in no particular order.

OSF HealthCare named one of America’s Most Innovative Companies – Fortune recognized OSF for its innovation culture and forward-thinking approach, highlighting digital and AI-driven advancements transforming care delivery. OSF first received this distinction in 2023.

OSF Innovation brings VR beating hearts to life for safer surgeries – Thanks to a breakthrough at OSF Innovation, surgeons can “see” their patient’s heart beating in 3D before ever stepping into the operating room. For surgeons, the benefits are game-changing. They can see not only the anatomy but also how it changes with every beat. This is especially critical for conditions such as hypertrophic obstructive cardiomyopathy, where the problem lies in how the heart contracts. Even more surprising, the AI began rendering valves — structures notoriously difficult to see on CT scans.

An OSF inventor collaborates to help kids play safely through cancer – Exercise physiologist Nick Kemp collaborated with OSF Innovation Studio to design Port Guard that protects the central venous access port for kids with cancer who want to play and stay active. Seven-year-old Amaneigh Stevenson, pediatric cancer patient, was part of testing and declared, “It makes me feel safe. I love it a lot.”

OSF developing app to diagnose migraines sooner and more accurately – For millions of people living with migraine headaches, getting the proper diagnosis can take years, sometimes even decades. A new digital tool developed by a team at the University of Illinois College of Medicine Peoria (UICOMP) and OSF HealthCare aims to change that by helping primary care and other first-contact healthcare providers to identify patients with migraine quickly and accurately.

Decoding your DNA to prevent disease – Using innovative genetic testing, OSF HealthCare stepped farther into personalized medicine in 2025, with a pilot to allow people to be tested with just a swab of their cheek for genetic mutations to determine if someone is at high risk of any of 10 major diseases. So called polygenic testing is not yet covered by insurance but for someone with a a family history of heart disease, cancer or Alzheimer’s, this $250 test could provide some early warning signs and better yet, early intervention.

Imagine being a heart surgeon preparing for a complex case. Traditionally, you rely on stacks of 2D images from CT scans to build a mental picture of your patient’s anatomy. But the heart isn’t static – it twists and pumps blood in a rhythm unique to each person. Now, thanks to a breakthrough at OSF Innovation, surgeons can “see” their patient’s heart beating in 3D before ever stepping into the operating room.

This innovation is called the 4D Heart. Unlike standard 3D models, which capture a single snapshot in time, the 4D Heart recreates every phase of a patient’s cardiac cycle, allowing doctors to watch their heart beat virtually. And it isn’t just a generic animation. Rather, it is the creation of a digital twin.

“This is taking a CT scan of a patient, a retrospectively gated CT scan, and converting a patient’s own heart – in each phase of that cardiac cycle – and making it beat in a virtual environment,” says Matthew Bramlet, MD, who directs the Advanced Image and Modeling (AIM) Lab at OSF Innovation. The lab is focused on improving the understanding of complex anatomy for surgeons and diagnosticians. Dr. Bramlet also specializes in congenital cardiac MRI for OSF HealthCare Children’s Hospital of Illinois and is an associate professor of Clinical Pediatrics at the University of Illinois College of Medicine in Peoria and the University of Illinois Grainger College of Engineering in Urbana-Champaign.

Dr. Bramlet’s efforts began in 2018 with manually segmenting parts of the heart so it could be viewed in virtual reality. It continued with an infusion of grant money two years ago. Using an Innovation for Health (IFH) grant with Bradley University in Peoria, Illinois, a team used machine learning to convert standard medical images into a sequence of 3D models that, when played sequentially, create a 3D beating heart – the 4D heart. The initial process took an entire summer.

That made the technology nearly impossible to use in real world clinical care. But in late 2024, researchers achieved a major breakthrough. With the help of engineers at the University of Illinois Urbana-Champaign, AIM lab engineers trained neural networks on hundreds of high-quality CT scans and automated the entire process. Now, what once took months can be done with a single click.

“Have you ever seen a flip book where you see a drawing move? That’s what we’re doing with these 3D models in a digital, virtual space.” Dr. Bramlet explains, “We’re just turning them off and on in rapid succession until we have that beating heart.”

For surgeons, the benefits are game-changing. They can see not only the anatomy but also how it changes with every beat. This is especially critical for conditions such as hypertrophic obstructive cardiomyopathy, where the problem lies in how the heart contracts. Even more surprising, the AI began rendering valves — structures notoriously difficult to see on CT scans.

“Now we can see that valve which we really couldn’t see before. So, repeat valve procedures are very valuable for this. TAVR or any valve in the cath lab, we’re finding good use with these as well as the hypertrophic cardiomyopathy cases.”

Hospitals across the country are taking notice, sending scans to OSF and receiving beating heart files in return. Some don’t even have the technology to view them yet. Dr. Bramlet says OSF Innovation is pushing the boundaries so far forward, some other health systems will need to get on board with the technology to be able to visualize the data being sent to them.

For now, the ability to view a 4D Heart is already changing how surgeons think about the body’s most vital organ. In some cases, the new view is confirming a surgery plan. In other cases, including a most recent pediatric heart case from another hospital, it changed the approach. Dr. Bramlet says as surgeons interact with the models, they are amazed.

He shares, “I see those lightbulbs go on and there’s nothing like being able to observe and interact with these 3D models in a format, and especially a 4D model, in a way they’ve never been able to see them before, and it will become the standard of care, I have no doubt.”

The ultimate vision is bold: a patient enters the CT or MRI scanner, and their digital twin heart comes out the other side – ready for analysis, surgical planning and even analysis of AI-driven measurements like ejection fraction or blood flow strain to help with diagnosis and a treatment plan.

How long until that happens? Hard to say because as Dr. Bramlet points out, “seeing is believing,” and it might take time for health systems to invest in the technology to make the vision become reality. Government reimbursement for the care will also drive adoption. For now, the work is being covered through research grants, most notably; the Jump ARCHES endowment through the Health Care Engineering Systems Center at the University of Illinois Urbana Champaign and OSF HealthCare.

Dr. Mathew Bramlet

B-roll-4D Beating Heart

OSF HealthCare and Bradley University are focusing on cancer prevention and treatment, as well as improving overall cardiac imaging plus pulmonary lung monitoring for babies and young children. The grants are the result of a partnership announced earlier this year between the Peoria, Illinois-based health system and the city’s premiere private university. The awards be given twice a year with joint funding from each organization.

This first round of grants, totaling nearly $200,000, have been awarded to four projects for research into rapidly developing the best, innovative approaches to medical training and health care delivery. The IFH grant awards include co-investigators from both Bradley University and OSF HealthCare.

Here are the Innovation for Health projects for spring 2023:

Toward Automation of a 4D Heart from Retrospectively Gated Cardiac CT Scans

Lead researchers
Matthew Bramlet, MD, OSF HealthCare
Samuel Hawkins, PhD, Bradley University

The goal of this project is to determine the feasibility automating the segmentation of the 18 phases of gated cardiac CT scans to generate patient-specific, 4D beating hearts and that these 4D animations can be placed into and analyzed in a digital stereoscopic format such as virtual reality.

Pulmonary Acoustic Sensor Telemetry Array (PASTA)

Lead researchers
Adam Cross, MD, FAAP, OSF HealthCare
Suruz Miah, PhD, Bradley University
Connor Davey, BA, OSF HealthCare
Reid Jockisch, BS, OSF HealthCare

This venture is an expansion of the Pulmonary Acoustic Sensor Telemetry Array (PASTA) project which is focused on developing a device for use with an algorithm to remotely monitor lung sounds in pediatric patients. The primary deliverable of this phase is a physical device that is easily replicable and records eight channels of audio simultaneously without losing quality due to compression with minimal quality loss due to compression.

Characterization of Changes in Biomechanical Properties and Cell Aggression in Ovarian Cancer Stem Cells Following Exposure to Chemotherapy

Lead researchers
Kalyani Nair, PhD, Bradley University
Craig Cady PhD, Bradley University
Daniel Chan, MD, PhD, OSF HealthCare

The objective of this concept is to determine whether treatment with a chemotherapeutic agent will induce identifiable changes in the biomechanical properties of cancer stem cells which can be correlated with an increase in cancer stem cell aggression. Identifying biomechanical properties linked to an increase in aggression may suggest alternative approaches to suppressing cancer stem cell activation and reducing the recurrence of cancer.

Humanizing Breast Cancer Prevention: A Community-Based Approach to Increase Health Literacy and Address Breast Cancer Health Disparities among Local Underserved Women

Lead researchers
Heather Ford, MFA, Bradley University
Scott Barrows MA, FAMI, OSF HealthCare
Tianjiao (Grace) Wang, PhD, Bradley University|
Rachelle Pavelko PhD, Bradley University
Mary Stapel, MD, OSF HealthCare

This project aims to address health disparities among underserved groups by developing a community-based solution to effectively increase breast cancer health literacy and raise awareness of breast cancer prevention among local ethnic minority women.