OSF HealthCare named one of America’s Most Innovative Companies
Second time for designation by Fortune
Key Takeaways:
- OSF ranked 264 overall out of 300 companies recognized nationwide
- OSF saw an improvement in its culture and process scores from 2023
- Organizations were assessed in three key areas: product innovation, process innovation, and innovation culture.
OSF HealthCare has once again been recognized by Fortune as one of America's Most Innovative Companies for 2025. OSF first received this distinction in 2023.
This ranking is highly competitive, with only the top 300 companies selected from thousands analyzed. Winners were determined by Fortune and Statista, the world-leading statistics portal and industry ranking provider, through a rigorous evaluation process that included a survey of 40,000 U.S. employees and 2,500 industry experts, as well as patient data and expert advisory board reviews. Organizations were assessed in three key areas: product innovation, process innovation, and innovation culture.
Of the 300 U.S. companies with the highest score awarded by Fortune as America’s Most Innovative Companies 2025 OSF was rated at 264 overall with an improvement in its culture (249) and process (202) scores from 2023. OSF was the only health care system in Illinois to make the list.
The recognition highlights significant strides by OSF in integrating forward-thinking solutions to enhance patient care and operational excellence.
This honor reaffirms that innovation isn’t just something we do — it’s who we are,” said Bob Sehring, CEO of OSF HealthCare. “From groundbreaking treatments to AI-driven advancements, OSF is leading the charge in transforming health care.
“This honor reaffirms that innovation isn’t just something we do — it’s who we are,” said Bob Sehring, CEO of OSF HealthCare. “From groundbreaking treatments to AI-driven advancements, OSF is leading the charge in transforming health care.”
OSF HealthCare continues to make headlines for pioneering advancements, including:
- A historic first: Successfully implanting the world’s first extravascular implantable cardioverter-defibrillator (EV-ICD) in a 2-year-old patient who suffered sudden cardiac arrest.
- Faster, seamless cancer care: Launching a rapid access program at OSF Cancer Institute to speed up and streamline patient access.
- At-home pediatric monitoring: Developing a program for RSV and other respiratory illnesses to reduce hospital visits.
- AI-powered rare disease detection: Utilizing AI and Large Language Models to enhance primary care diagnostics.
- Revolutionizing concussion diagnosis: Creating FlightPath, a cloud-based app that uses AI and eye-tracking to diagnose concussions within minutes.
- Enhancing clinical efficiency: Piloting AI-driven software that listens to clinician-patient conversations and generates real-time clinical documentation.
- Advancing early cancer detection: Testing AI technology to improve the identification of potential cancerous polyps during colonoscopies.
- Shaping the future of AI in health care: As one of 38 payers and providers partnering with the White House, OSF is helping define responsible AI-driven change in the industry.
“Since our founding in 1877, innovation has been the heartbeat of our Mission,” said Michelle Conger, president of OSF HealthCare. “Being named one of America’s Most Innovative Companies for the second time reflects our relentless pursuit of cutting-edge solutions, from leveraging AI to empowering our frontline Mission Partners to bring transformative ideas to life.”
Learn more about America’s Most Innovative Companies and the Fortune recognition, visit Fortune.com.
To explore how OSF is reshaping the future of health care, tune in to the OSF HealthCare Accelerated podcast on Spotify, Google, and Apple Podcasts.
OSF HealthCare is an integrated health system founded by The Sisters of the Third Order of St. Francis. Headquartered in Peoria, Illinois, OSF HealthCare has 17 hospitals – 11 acute care, five critical access, one continuing care – with 2,305 licensed beds throughout Illinois and Michigan. OSF employs more than 26,000 Mission Partners across 160+ locations and includes OSF OnCall, the digital health operating entity which offers a hospital-at-home. Advances in health care transformation take place through OSF Innovation and OSF Children’s Hospital of Illinois, the third largest pediatric hospital in Illinois, cares for our smallest patients. In addition, OSF has two colleges of nursing; operates OSF Home Care Services, an extensive network of home health and hospice services; owns Pointcore, Inc., comprised of health care-related businesses; OSF HealthCare Foundation, the philanthropic arm for the organization; and OSF Ventures, which provides investment capital for promising health care innovation startups. OSF HealthCare has been recognized by Fortune as one of the most innovative companies in the country. More at osfhealthcare.org.